Amoxicillin in tablet, capsule or syrup powder form.

Action
Amoxicillin is an antibacterial drug of the beta-lactam family of the aminopenicillin group.

Indications

Antibacterial used in the treatment of:
Otitis
Acute bronchitis
Acute pneumonia
Chronic bronchitis
Digestive and biliary infection
Sinusitis
Genital infection
Urinary infection
Angina
Bacterial endocarditis
Eradication of Helicobacter in combination with clarithromycin or imidazoles
Stomatological infection
Lyme disease
Endocarditis

Dosage
Adult: 1 to 2 g per day divided into 2 or 3 doses
Children under 30 months: 50 to 100 mg per kilo per day in three doses spaced eight hours apart.
Children over 30 months: 25 to 50 mg per kilo per day in two or three doses without exceeding 3g per day.
In cases of endocarditis and septicemia, the dosage is sometimes increased to 150 mg per kilo per day in 3 or 4 doses without, however, exceeding 6 g per day.
In case of streptococcal angina in children over 30 months, it is necessary to carry out a 6-day treatment at a dosage of 50 mg per kilogram per day in two doses.

Contraindications
Infectious mononucleosis
Allergy to beta-lactam antibiotics (penicillin and cephalosporin) as well as to one of the components of the drug
Phenylketonuria (due to the presence of aspartame)

Warnings

Risk of allergy occurrence
Need for sufficient water intake
Risk of occurrence of severe anaphylactic-type hypersensitivity
Usefulness of adjusting the dosage in case of renal insufficiency
Risk of Jarisch-Herxheimer reaction in treatment of Lyme disease

This medicine contains sodium: this should be taken into account in patients with high blood pressure or those on a salt-free diet.

Amoxicillin should not be combined with the following medications:
Methotrexate
Allopurinol (risk of skin reaction)

Precautions

Possible interferences: determination of total serum protein levels by color reaction
In diabetics in particular, amoxicillin may decrease blood sugar test results.
Amoxicillin may give a false-positive color reaction in urine glycosuria assays by the semi-quantitative colorimetric method.
Precautions are necessary in case of renal failure
As for the injectable preparation, the solvent should not be used in children under 3 years of age because it contains benzyl alcohol.

Pregnancy and breast feeding
This medication is not recommended during pregnancy and breastfeeding.

Adverse reactions

Allergic manifestation
Nausea
Bullous or exfoliative dermatitis
Troubles digestifs
vomiting
Erythema multiforme
Maculo-papular rash
Stevens Johnson Syndrome
Pseudomembranous colitis
Acute interstitial nephritis
Diarrhea (this is the case with many antibiotics. If significant diarrhea occurs during the days following the start of antibiotic treatment, the treatment should be stopped)
Candidiasis
Reversible thrombocytopenia
Moderate and transient increase in transaminases
Anemia
Leukopenia

Please note:
A decrease in hyperthermia (fever) or the disappearance of symptoms should not lead to discontinuation of treatment. Indeed, there is a risk of the germ developing resistance to this antibiotic.