Definition
Definition
Fibrinogen is a protein found in blood plasma produced by the liver and plays an important role in blood clotting. It is converted into fibrin by the action of another protein, thrombin, which is a blood protein capable of activating fibrin.
Symptoms
physiology
Fibrinogen, also known as coagulation factor I, is a precursor to fibrin . It is part of a cascade that constitutes the complex mechanism of blood coagulation in general. When thrombin activates fibrinogen, it is transformed into fibrin, which then polymerizes , meaning that numerous monomers (fragments) adhere to one another, becoming insoluble and thus stabilized by the action of another factor, factor XIII . From this point, a set of proteins is formed, constituting a kind of plug whose purpose is to stop the bleeding: this is the closure of the wound.