Definition
Definition
Fibrin is a blood plasma protein produced by the liver and playing a key role in blood clotting.
Generalities
Fibrin is obtained from fibrinogen , which is also a protein produced by the liver and is part of a cascade that constitutes the complicated mechanism of blood clotting.
Thrombin , another element involved in blood clotting, is a blood protein capable of activating fibrin.
When thrombin has activated fibrinogen, the latter is then transformed into fibrin, which will then polymerize, that is to say, carry out the joining of many monomers (pieces), and become insoluble because it has acquired a stabilization thanks to the intervention of another factor ( factor XIII ).
From there, a set of proteins is brought together, forming a sort of plug whose purpose is to stop the bleeding: this is the sealing of the wound.