Definition
Definition
Abiotinosis is a very rare disease caused by a deficiency of biotin (vitamin B8 or vitamin H).
It most often occurs when administering infusions in which there is no, or not enough, vitamin B8.
Sometimes it is a hereditary disease of the functioning (metabolism) of this vitamin, during which certain enzymes such as biotinidase or holocarboxylase synthetase are missing.
Symptoms
Symptoms
Symptoms of abiotinosis are:
- An inflammation of the skin that "peeles".
- An inflammation of the tongue (glossitis).
- A grayish pallor.
- Intense fatigue (asthenia).
- Loss of appetite (Anorexia).
- Nausea.
- Convulsions.
- Pain in the muscles (myalgia).
- Sensitivity disorders (paresthesias).
- Hair loss.
Treatment
Treatment
Treatments for abiotinosis are:
- La biotin is found mainly in foods rich in egg yolk, in yeast, meat, dairy products, kidneys, certain vegetables, and in the liver. It is a water-soluble vitamin, i.e. soluble in water. It is involved in the breakdown of fatty acids (basic constituents of certain fats), but also in the synthesis of certain amino acids (basic elements constituting proteins), and glucose (sugar). Needs are around 50 to 90 micrograms per day during childhood and 100 to 300 micrograms per day from adolescence.
- La vitamin B8 is synthesized in part by the intestinal flora.